Jitsi 2.0

Probably the most feasible Skype-replacement for all just released version 2.0:

Among the most prominent new features you will find quality multi-party video conferences for XMPP, audio device hot-plugging, support for Outlook presence and calls, an overhauled user interface and support for the Opus and VP8 audio/video codec.

Get Jitsi. If you don’t, watch Free, open, secure and convenient communications: Can we finally replace Skype, Viber, Twitter and Facebook? as mentioned previously.